Benzos, Carisoprodol, barbiturates, antihistamines, antipsychotics, weed (can increase or decrease anxiety), alcohol, gabapentoids (phenibut, baclofen, pregabalin, gabapentin), beta blockers (propranolol), CBD, a1 antagonists, a2 agonists, TCA’s, ssri and snri (long term use), trazodone, 5HT1A agonists (long term), a heavy introspective trip on psychedelics leading to profound discoveries of yourself and healing anxieties (lol), certain herbal supplements like valerian root or ashwagandha, supplements like magnesium or l-theanine, kava, kratom, some peptides, some hormones, the list is extensive and depends on so many things, some are more risky than others.