Mephedrone (4-MMC) Synthesis [2B4M, Etyhyl Acetate, Methylamine HCl]

[c01db100d_india_mephedron]

Can we replace

MA HCI to
METHYLAMINE (mono) 40%
CAS.No: 74-89-5

Ordered

2-Bromo-4-methylpropiophenone 1451-82-7
Acetate
NaOH
Acetone


Tell me if we need something more ?

 

[Dr. MMX]

hcl acid, i didnt note it in reagents, my mistaker
hcl acid is needed as well

 

[c01db100d_india_mephedron]

I tried but they look like and final quantity we get only 10g.
Plz check attachment and it's good or not.What I made tastes like salt, is that right?

Refrance video.

Mephedrone hydrobromide synthesis

Mephedrone hydrobromide synthesis from 2-bromo-4'-methylpropiophenone with n-methylpyrrolidone https://bbgate.com/threads/synthesis-of-mephedrone-in-nmp-large-scale.231/

bbgate.com

@Dr. MMX @$!$

 

[Dr. MMX]

What is it? is it mephedrone you received in the end?
provide more details what you used and what you did

 

[c01db100d_india_mephedron]

Yes it is,
I do every step and chemical quantity
From this video

Mephedrone hydrobromide synthesis

Mephedrone hydrobromide synthesis from 2-bromo-4'-methylpropiophenone with n-methylpyrrolidone https://bbgate.com/threads/synthesis-of-mephedrone-in-nmp-large-scale.231/

bbgate.com

 

[Dr. MMX]

i believe you should describe it yourself, becasue if you did exactly the same, the result would be the same as well so you had to misssomething. Check it again

 

[c01db100d_india_mephedron]

I type in pm ,what i do. Give 5 min

 

[TucoSalamanca.]

metilamini eklerken kaç dereceyi geçmemeli

 

[TucoSalamanca.]

ve eklerken soğuk su banyosu mu yoksa sıcak mı

 

[Dr. MMX]

Please use english, so others may understand as well.
max 55-60 degrees
its cold bath, water from fridge is ok
remmeber to not put bath before bk4 is disolved in EA becase it may cool down to not let it dissolve if its not crushed well

 

[TucoSalamanca.]

bu reaksiyonda % kaç sodyum karbonat kullanıyım

 

[Dr. MMX]

please bro just translate it to english 1st. Its english forum, wjhy do force othjers to translate ur language to understand?

 

[TucoSalamanca.]

I thought I thought the forum was translating, I apologize, how many % sodium carbonate should I use in this reaction?

 

[Dr. MMX]

sodium bicarbonate.
I use 5% solution so 285 ml H2O pure and 5% NaHCO3, but its after reaction

for reaction you use NaOH with water chilled then added with HCL methylamine.

 

[cannedgoodsvendor]

nice stuff

 

[TucoSalamanca.]

how many degrees should it be when we add methylamine?

 

[TucoSalamanca.]

and how many ml of acetone and how many ml of hcl did you use in this synthesis?

 

[Dr. MMX]

you care about to have it less than 55, cant really exceed 60
it dpeensd what amount you add, what bath size u have flask size etc, many factors but improtant iis the not exceeding it - the far the better

u add 1:1 of remaining freebase in EA, ifu have 500 ml u add 500 ml. it depenjds how m,uch acid, usually per 100bk4 and 500 ml ea used in the 1st its 50-70 ml of 37 % pure HCL, depends u must measure it to be sure, but always measure "good chemist is an accurate chemist"

 

[TucoSalamanca.]

I am not a chemist but I have good organic chemistry

 

[TucoSalamanca.]

What should be the pH?

 

[Dr. MMX]

ph 5 is good
then if ur interested in chemistry i can show you book I like. I uploaded it. its nice to read https://bbzzzsvqcrqtki6umym6itiixfhn....torify.net/resources/organic-chemistry-book.4762/

 

[TucoSalamanca.]

How many g of 2-iodo-4'-methylpropiophenone should be used in this synthesis can you write the whole calculation?

 

[Anarchy Labz]

It would be awesome to have a video of this synthesis

 

[Osmosis Vanderwaal]

There is one, in the video section. Exactly this

 

[WalterFan]

May I have a question about the ma.HCI part ? I’ve watched your post about adding ma.HCI directly into the mixture, and I also try it once recently, I have a problem when I dissolved the 2b4m in solvent, should I followed with NaOH + water and start stirring, then adding MA.HCI immediately with small portions? If I didn’t misunderstand it, the whole mixture would turn dark after adding NaOH water, it’s happening before any MA.HCI followed, because it was what happened during my synthesis, so am I did anything wrong ? Or it is normal ? Best regards

 

[Dr. MMX]

yes exactly as in description
plaese type steps what you exactly did like in my topic
do the same