The Simplest recipes

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Breaking Bad introduces you to the world of making drugs with your own hands. In the Synthesis technologies and analysis section we offer a variety of synthesis techniques, research and testing methods. Almost all of these methods have been tested by us in practice, all of them are working schemes. An experienced chemist will have a good understanding of most of the cooking methods and will have no difficulty with the cooking methods.

But what about people who want to make drugs but aren't sure how?
What if you have trouble with chemistry and are afraid to cook, even with simple step-by-step instructions from the synthesis section?
You're understandable! In fact, to the untrained eye, all of this may appear to be complicated.

For this purpose, we have decided to create a new section called "The simplest recipes", where we will show the simplest synthesis technologies for the most popular substances. In this section, we will try to explain each step in as much detail as possible, without emphasizing chemical terms, incomprehensible formulas, and other technical jargon. Only the easiest to understand recipes so you can successfully cook the product in your kitchen or garage. The result will surprise you: Cooking quality drugs is actually very easy and quick!

We are ready to provide you with full support at every stage of the cooking process. Feel free to ask questions in this section or send private messages to the forum administrators. We're always going to help you get started, finish cooking, and sell what you make! Try it, don't be afraid, it's really easy!

Which syntheses of which substances would you like to see in this section?
What synthesis instructions should we try to simplify for you? Write in this thread.
 

mocnykutas

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3/4mmc 3/4cmc apvp/MDPvP bk mdma speed form a oil
 

Frit Buchner

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😬😬😬😬 this is an interesting concept. I thought you were bullshiting, but you have that staff placard.
I don't even know what to suggest. How about a phenyltropane, WIN series, RTI, Troparil, or RTI? How can I chop about 10 hydrocarbons off of this benzonotate, and methylate it? This isn't a new idea but every topic I've seen like this was immediately dead in the water because no one could come up with a SINGLE SYNTH except maybe chloroform choral hydrate and extracting plants, which is not synthesis. I'd be happy to see anything.
HEY tell me what I can do with this bag of b- phenylethylamine HCL 500g!?!!
 

Benz88

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Methamphetamin .
 

pachemguy

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I would love to see a guide for the Pyro compounds showing the different sub of which phenone correspond with each come compound (a-php=valerophenone, mdpv= etc). Also would be amazing to see some simple disso/phsy compounds synthesis (mxe,fxe,pcx,) type compounds also and 2cx or substituted triptimines
 

41Dxflatline

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Bupropion
 

BevItUp

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the right stuff

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This has to be the most empowering experience I've had in a while. I've a bottle of base tryptamine that I would like to do some alchemy with. Guidance on what to do with it would be awesome.
 

Frit Buchner

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41Dxflatline

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A quick peek suggests 4-aco is a prodrug of 4-ho. So, in vivo they are identical, in vitro 4-ho is a little more potent w/w. Where lies the advantage?
Frit Buchner4-HO is a probable metabolite of 4-ACO but a prodrug is something inactive, 4-aco is active in its own right. There's also a more going on in its metabolism including metabolites that are not present from 4-HO
 

Frit Buchner

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I must admit, your casual glib appears to be pure hyperbole. I couldn't find a single reference that claimed, with any authority, that 5-meo is active, although there's no reason it wouldn't be. All of the references to metabolites were hidden behind a pay wall, but the summary was that first pass metabolism highly digests it. The only real way to settle this is to synthesize 2-a,4,5-homo- DIMET phosphoric acid dimethylamide and shoot it up
 

41Dxflatline

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I must admit, your casual glib appears to be pure hyperbole. I couldn't find a single reference that claimed, with any authority, that 5-meo is active, although there's no reason it wouldn't be. All of the references to metabolites were hidden behind a pay wall, but the summary was that first pass metabolism highly digests it. The only real way to settle this is to synthesize 2-a,4,5-homo- DIMET phosphoric acid dimethylamide and shoot it up
Frit BuchnerI have references. I mean you've clearly seen these references also to decide to qualify them as "without any authority". But I'd like to know why you're discounting them?

Also I'm not sure what this means "All of the references to metabolites were hidden behind a pay wall, but the summary was that first pass metabolism highly digests it" first pass mechanism isn't really relevant in any way. First pass isn't a single instance of a singular transformation. Multiple things can happen to the same compound in varying amounts. The evidence of unique metabolites is weak due to being in vitro but your assumptions that there aren't any seems to be based on a misunderstanding of first pass which can be bypassed anyway...
 

Frit Buchner

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The references were just researchers saying other researchers suggest that it might be active. There is no imperical data or personal experience reporting. No brain scan mri, or chemical or activity analysis.
Metabolic pathways and products hidden behind a pay wall means I can read the outline or summary, but Wiley online or research gate ect. Want me to pay $30 or something to see the entire document. I believe one paper eluded to 13 first pass metabolic processes, so yeah I'm aware there is more than 1.
MAO-a renders nn dmt inactive. MAO-b renders Phenylethylamine inactive. These are metabolic processes. To suggest that first pass metabolism is irrelevant is....insane. sure, you could shoot it up or smoke it to bypass some processes but I wouldn't say that makes it "irrelevant "
 

41Dxflatline

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The references were just researchers saying other researchers suggest that it might be active. There is no imperical data or personal experience reporting. No brain scan mri, or chemical or activity analysis.
Metabolic pathways and products hidden behind a pay wall means I can read the outline or summary, but Wiley online or research gate ect. Want me to pay $30 or something to see the entire document. I believe one paper eluded to 13 first pass metabolic processes, so yeah I'm aware there is more than 1.
MAO-a renders nn dmt inactive. MAO-b renders Phenylethylamine inactive. These are metabolic processes. To suggest that first pass metabolism is irrelevant is....insane. sure, you could shoot it up or smoke it to bypass some processes but I wouldn't say that makes it "irrelevant "
Frit BuchnerIt absolutely is irrelevant to whether it's active or not when it can be bypassed. Are you high or something? By your own weird criteria of whats active or not you're saying DMT is inactive and that's an absolutely insane thing to say.
 

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Frit Buchner

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It absolutely is irrelevant to whether it's active or not when it can be bypassed. Are you high or something? By your own weird criteria of whats active or not you're saying DMT is inactive and that's an absolutely insane thing to say.
41DxflatlineAre you high or something? Shit yes, stayed up all night learning about chirality and resolution of enantiomers and stereoisomers. At least you did post something that looks legitimate. IC50 of 100nm, for ht-5a? Are you sure you even want to call that active? It certainly doesn't compare to psilocin. Having to take 10x as much doesn't seem like an advantage, but then again tryptamines are my least favorite drug, so maybe it is 🤔. Dmt isn't orally active. Need those qualifying adverbs.
 
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41Dxflatline

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Are you high or something? Shit yes, stayed up all night learning about chirality and resolution of enantiomers and stereoisomers. At least you did post something that looks legitimate. IC50 of 100nm, for ht-5a? Are you sure you even want to call that active? It certainly doesn't compare to psilocin. Having to take 10x as much doesn't seem like an advantage, but then again tryptamines are my least favorite drug, so maybe it is 🤔. Dmt isn't orally active. Need those qualifying adverbs.
Frit BuchnerIt's definitely of a different character to eating mushrooms if you snort 4-aco as opposed to eating it to most who have tried it. Of course, you don't have to take 10x as much since you still get the psilocin metabolite as well along with any others. DMT isn't orally active because of first pass, which is why I was telling you first pass is irrelevant to whether something is active or not. Anyway, even if all things were equal between psilocin and 4-aco-dmt in regards to effect 4-aco-dmt would still be superior because it's far more stable.

There's a few anecdotes of how snorting 4-aco-dmt is different in this reddit thread:

https://www.reddit.com/r/4acodmt/comments/ma6lyc
 

the right stuff

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I'll give you even odds that if you put spores of a psilocybe species on cow droppings loaded with 5-MeO-DMT you would come out with mushrooms containing 4,5-HO-MeO-DMT. This way you avoid a 10 step synthesis by growing a psychoactive mushroom that contains no illegal drug.”
-shulgin
 

Frit Buchner

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I'll give you even odds that if you put spores of a psilocybe species on cow droppings loaded with 5-MeO-DMT you would come out with mushrooms containing 4,5-HO-MeO-DMT. This way you avoid a 10 step synthesis by growing a psychoactive mushroom that contains no illegal drug.”
-shulgin
the right stuffI'll have To write this out but I'm going to say no, you wouldn't get that as a product
 
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